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优糖性酸性酸症 后袖胃切除术在2名1型糖尿病患者中使用自动化胰岛素输送
Wedyan M Aboznadah1,2, Michael A Tsoukas1,3,4, Xiao Wen Hu1,3
1Division of Endocrinology, McGill University Health Centre, Montréal, QC, Canada H4A 3J1.
JCEM case reports
|March 20, 2025
概括
接受减肥手术的1型糖尿病患者在手术后面临euglycemic ketoacidosis的风险. 先进的胰岛素输送系统可能有助于管理这种风险,但警仍然至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 代谢手术 代谢手术
- 糖尿病管理 糖尿病管理
背景情况:
- 在1型糖尿病 (T1D) 中肥胖率的上升导致肥胖手术的增加.
- 手术后的糖尿病酸性酸症 (DKA),特别是euglycemic DKA,在减肥手术后的T1D患者中是一个显著的风险.
- 自动化胰岛素输送系统 (AID) 在T1D管理中提供了好处,但并不能消除DKA风险.
研究的目的:
- 在使用AID的T1D患者中,在袖子胃切除术后报告轻度euglycemic ketoacidosis的病例.
- 为了突出这一群体中DKA的持续风险,尽管技术进步.
主要方法:
- 一系列病例描述了两名患有T1D和肥胖的成年人接受袖子胃切除术.
- 使用商业自动化胰岛素输送系统进行密集胰岛素治疗.
- 在术后期间监测糖尿病酸性脂肪酸.
主要成果:
- 在术后观察到两例轻微的euglycemic ketoacidosis病例.
- 患者在酸发生时使用自动化胰岛素输送系统.
- 在这两种情况下,袖子胃切除术是外科手术.
结论:
- 在T1D患者的低血糖手术后,即使有AID,euglycemic ketoacidosis仍然是一个风险.
- 来自AID技术的数据有可能改善风险识别和预防策略.
- 持续监测和意识是管理T1D患者进行腹部外科手术的必要条件.
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