1型糖尿病儿童和青少年的时型,睡眠和血糖控制:一个病例对照研究
Gulay Can Yilmaz1, Mehmet Karadag2
1Department of Pediatric Endocrinology, 175646 Muğla Sıtkı Koçman University, Faculty of Medicine , Muğla, Türkiye.
Journal of pediatric endocrinology & metabolism : JPEM
|March 20, 2025
概括
患有1型糖尿病 (T1DM) 的儿童睡眠质量较差,时间类型较晚,影响血糖控制. 解决睡眠问题对于管理青少年T1DM至关重要.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 睡眠医学 睡眠医学
- 代谢健康 代谢健康
背景情况:
- 儿童和青少年的1型糖尿病 (T1DM) 管理需要了解影响血糖控制的因素.
- 睡眠障碍和时间型偏好越来越多地被认为是代谢失调的潜在贡献者.
研究的目的:
- 为了研究儿童T1DM患者与健康对照者之间的睡眠参数,时间型和血糖控制 (HbA1c) 之间的关联.
- 在这个人群中确定与睡眠相关的低最佳血糖控制的预测因素.
主要方法:
- 一项涉及96名患有T1DM的儿童和青少年和95名健康对照 (8-18岁) 的病例控制研究.
- 数据收集包括人体测量,慕尼黑时刻型问卷,匹兹堡睡眠质量指数 (PSQI) 和HbA1c水平.
- 统计分析采用了逻辑回归和通用线性建模 (GLM).
主要成果:
- 患有T1DM的儿童的睡眠时间较短,睡眠质量较差,时间类型较晚 (p<0.05).
- 睡眠质量差 (OR: 1.47) 和晚期时间型 (OR: 5.14) 是血糖控制差 (HbA1c>7.5%) 的独立预测因素.
- GLM显示HbA1c,胰岛素剂量和时间型之间存在显著的关联.
结论:
- 晚期时刻型和睡眠质量差与儿科T1DM中低于最佳的血糖控制有显著联系.
- 这些发现强调了将睡眠评估和干预措施纳入青少年T1DM管理策略的必要性.
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