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Updated: May 21, 2025

Brain Slice Biotinylation: An Ex Vivo Approach to Measure Region-specific Plasma Membrane Protein Trafficking in Adult Neurons
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功能性选择性多巴胺D1受体内细胞和信号由catechol和noncatechol激动剂

Ashley N Nilson1,2, Daniel E Felsing3,2, Pingyuan Wang3,4,2

  • 1Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555-0615, United States.

Biochemistry
|March 20, 2025
PubMed
概括

新的非catechol多巴胺D1受体 (D1R) 激动剂显示偏差信号,影响受体内细胞化. 均衡的激动因子促进D1R内细胞分裂,而偏向的激动因子没有,揭示了功能选择性.

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