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Updated: May 21, 2025

Extraction and Analysis of Taiwanese Green Propolis

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巴西和中国的组成差异

Sierra R Parkinson¹, Francelia J Eckembrecher², Lazaro Antonio Toledo Machin³

¹From the University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.

Dermatitis : contact, atopic, occupational, drug

|March 20, 2025

概括

最近气过敏反应的增加与巴西气和中国气之间的组成差异有关. 化学构成的这些变化可能解释了阳性贴片测试的增加.

科学领域:

分析化学分析化学
自然产品化学化学
皮肤病学皮肤病学

背景情况:

增加了对的阳性补丁测试反应的患病率.
反应速率的变化取决于 прополис制造商.

研究的目的:

为了比较巴西和中国的化学成分.
调查增加粉过敏患病率的潜在原因.

主要方法:

电子喷雾电离质谱仪 (ESI-MS) 用于样本分析.
使用 mzCloud,ChemSpider 和 MassList 数据库识别化合物.
使用Compound Discoverer软件进行数据处理,以识别顶级化合物.

主要成果:

巴西和中国的组成重叠非常低 (8-27%的相似性).
在每个类型中确定了不同的主要化合物集.
在两种样本中,Prenylgermacrene B是前六名中唯一常见的化合物.

结论:

巴西和中国之间存在显著的化学差异.
制造商停止使用中国 (NA71) 并用巴西 (NH400) 代替,这可能解释了过敏反应的增加.
化学变异性是与 прополис相关的接触性皮肤炎的一个关键因素.

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