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Updated: May 21, 2025

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome
11:15

Pooled shRNA Screen for Reactivation of MeCP2 on the Inactive X Chromosome

Published on: March 2, 2018

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全基因组沉声器查揭示了关键沉声器调节重编程效率在老鼠诱导的多能干细胞的干细胞

Xiusheng Zhu1, Lei Huang1, Guoli Li1

  • 1Shenzhen Branch, Guangdong Laboratory of Lingnan Modern Agriculture, Key Laboratory of Livestock and Poultry Multi-omics of MARA, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen, 518124, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|March 20, 2025
PubMed
概括

研究人员在老鼠基因组中发现了数千种新型基因沉默器. 这些对基因抑制至关重要的调节元素是细胞特异的,影响细胞重编程和多能性.

关键词:
这就是SS-STARR-seqq.这些是cis-regulatory元素.具有高通量功率的高通量功率.这些是iPSCs.沉声器是一种沉声器.

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