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Updated: May 21, 2025

Visualizing Clathrin-mediated Endocytosis of G Protein-coupled Receptors at Single-event Resolution via TIRF Microscopy
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下一代小分子抑制剂的克拉斯林功能急性抑制内细胞分裂

André Horatscheck1, Michael Krauß1, Haydar Bulut2

  • 1Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Rössle-Str. 10, 13125 Berlin, Germany.

Structure (London, England : 1993)
|March 20, 2025
PubMed
概括

新的Pitstop化合物通过向clathrin终端域,有效地抑制了克拉斯林介导的内细胞分裂 (CME). 这些下一代抑制剂显示细胞毒性降低,为研究细胞生理学和阻止病毒进入提供了更好的工具.

关键词:
凯瑟琳是什么意思 凯瑟琳是什么意思细胞内症是指内细胞内症.小分子抑制的抑制.病毒进入病毒.

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