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Updated: May 21, 2025

Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices
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Validation of Therapeutic Agent Conjugation to Polyvinyl Alcohol-Coated Medical Devices

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给药途径和PEGylation对α-1抗素增强疗法的影响

Xiao Liu1, Bernard Ucakar1, Kevin Vanvarenberg1

  • 1Université catholique de Louvain (UCLouvain), Louvain Drug Research Institute, Advanced Drug Delivery & Biomaterials, Brussels, Belgium.

Journal of controlled release : official journal of the Controlled Release Society
|March 20, 2025
PubMed
概括

吸入α-1抗素 (AAT) 增强疗法可能取代静脉输液治疗肺气. 肺部注射和PEGylation可以提高AAT的有效性和肺部暴露,同时保持稳定性.

关键词:
阿尔法1抗素是一种抗素.增强疗法是一种增强疗法.慢性阻塞性肺病是一种慢性阻塞性肺病.吸入式吸入方式通过PEGylation进行化.

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