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Updated: May 21, 2025

Partial Sciatic Nerve Ligation: A Mouse Model of Chronic Neuropathic Pain to Study the Antinociceptive Effect of Novel Therapies
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大麻醇通过激活脊髓PPARγγ来减少神经病痛和认知障碍

Ana Mara Islas-Espinoza1, Itzel I Ramos-Rodríguez2, María J Escoto-Rosales1

  • 1Neurobiology of Pain Laboratory, Departamento de Farmacobiología, Cinvestav, South Campus, Mexico City, Mexico.

The journal of pain
|March 20, 2025
PubMed
概括

大麻二醇通过激活脊髓氧酶增殖器激活受体玛 (PPARγ) 和5-HT1A受体,减少雌性小鼠的神经病痛和认知缺陷. 这项研究强调了它在治疗神经病痛和相关并发症方面的潜力.

关键词:
大麻二醇 (Cannabidiol) 是一种认知障碍 认知障碍是一种认知障碍.作用机制 作用机制神经病变性疼痛 神经病变性疼痛在PPARγ中,PPARγ是PPARγ

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