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检测和诊断呼吸中阿尔德海德生物标志物的技术方法:一篇综述

Taha Kafili-Hajlari¹, Abdolhossein Naseri², Atefeh Ansarin³

¹Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabri, Iran.

Analytical biochemistry

|March 20, 2025

概括

呼气分析显示了使用化物进行非侵入性疾病诊断的潜力. 研究正在推进这些重要呼吸生物标志物的收集和检测方法.

科学领域:

生物医学科学生物医学科学
分析化学分析化学
呼吸系统医学呼吸系统医学

背景情况:

呼气分析提供了一种非侵入性诊断方法.
化物是挥发性有机化合物 (VOC),具有作为疾病生物标志物的潜力.
低度和稳定性问题挑战了呼吸中的化物检测.

研究的目的:

审查最近关于呼吸阿尔德海德分析的研究.
专注于样本采集,分析技术和与疾病相关的发现.
为了指导未来的研究,在呼出的化物检测.

主要方法:

检查的呼吸采集方法:商业袋,潮尾采样,凝结物,直接分析.
评估的分析技术:气相色谱,质谱,微提取.
评估了用于实时检测的新兴微提取和传感技术.

主要成果:

呼吸中的化物变化与各种疾病有关.
微提取和传感方面的进步提高了实时检测能力.
目前的方法有希望,但面临局限性.

结论:

呼吸化物生物标志物对疾病诊断和查具有重大潜力.
为了克服目前的局限性,持续的研究是必不可少的.
本综述为未来的呼出化物分析工作提供了洞察力.

关键词:

分析技术分析技术生物标志物生物标志物呼吸中的阿尔德海德.检测检测检测检测检测疾病的诊断疾病的诊断

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