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Terrance Shoemaker1, Brendan R Amer2, Vladimir Razinkov2

  • 1Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, DE USA 19713.

概括

这项研究使用粗粒度模拟来模拟单克隆抗体 (MAb) 灵活性. 包括链灵活性在内对整体MAb相互作用的影响最小,这表明刚性模型对于大多数应用都足够.

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