在关节手术中,抗生素预防是否对术后感染有影响? - 进行系统审查
Nikoo Bazsefidpay1, Mattias Ulmner2, Erik Friman3
1Department of Oral & Maxillofacial Surgery, School of Medial Sciences, Faculty of Medicine and Health, Örebro University, SE, 70182, Örebro, Sweden.
概括
目前的证据不支持临时关节 (TMJ) 手术的抗生素预防. 需要更多的研究来制定明确的抗生素使用指南和预防耐药性.
科学领域:
- 口腔和牙面部外科手术
- 预防传染病 预防传染病
- 基于证据的医学基于证据的医学.
背景情况:
- 在关节 (TMJ) 手术中的抗生素预防有争议.
- 抗生素耐药性需要谨慎的建议,以防止过度使用和提高患者的安全.
研究的目的:
- 系统地审查有关抗生素在预防关节手术后术后感染的有效性的科学证据.
- 解决有关在关节手术过程中使用抗生素的知识差距.
主要方法:
- 在主要数据库 (科克兰图书馆,Medline,EMBASE,科学网) 中进行了全面的文献搜索.
- 系统性审查 (SR) 和初级研究是根据预先定义的标准进行选择的.
- 包含的研究的质量评估使用ROBIS进行了SR和GRADE用于初级研究.
主要成果:
- 在8976项已识别的研究中,只有两项在对20项研究进行全文审查后被纳入最终的系统性审查.
- 质量评估显示,包含的研究中存在普遍高偏差风险.
- 没有找到关于抗生素在关节手术后预防感染的有效性的确证据.
结论:
- 关于抗生素对关节手术中术后感染的影响存在重大知识差距.
- 进一步的研究至关重要,以制定基于证据的指导方针,用于关节手术中的抗生素预防.
- 目前缺乏证据阻止了推,强调了需要高质量的研究.
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