帕金森病语音产生的感官反:系统性审查
Francisco Contreras-Ruston1, Suvarnalata Xanthate Duggirala2, Judith Wingbermühle3
1Department of Cognition, Development and Educational Psychology, University of Barcelona, Barcelona, Spain; Faculty of Psychology and Neuroscience, Department of Neuropsychology and Psychopharmacology, Maastricht University, 6229 ER Maastricht, The Netherlands; Speech-Language Pathology and Audiology Department, Universidad de Valparaíso, San Felipe, Chile.
Journal of voice : official journal of the Voice Foundation
|March 20, 2025
概括
帕金森病 (PD) 通过改变感官反和大脑活动影响语音控制. 在了解PD患者的声音大声感知和情绪调制方面存在研究差距.
科学领域:
- 神经科学是一个神经科学.
- 语音语言病理学 语言病理学
- 神经学 神经学
背景情况:
- 声音和言语障碍在帕金森病 (PD) 中很常见.
- 了解这些障碍对于开发干预措施和改善PD患者的社交沟通至关重要.
研究的目的:
- 审查PD中语音感知和语音生成的研究结果.
- 专注于感官反,神经相关和语音质量参数 (音调,声音强度,情绪调制).
主要方法:
- 结合文献计量分析和系统审查.
- 专注于关于PD自我语音处理的神经成像文献 (fMRI/EEG).
主要成果:
- 脑电图研究显示了P200事件相关潜力的差异,与PD中的度有关.
- fMRI显示在PD发言过程中,运动皮层和基底腺节的激活发生变化.
- 减少右背前运动皮质的激活与语音控制受损有关,特别是声音调制.
结论:
- 关于PD中的声音大声感知存在显著的知识差距.
- 情感感知缺陷对PD语音调制的影响需要进一步调查.
- 改变的感官反对于PD患者发声中的补偿性皮质反应至关重要.
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