烟草使用对部分切除术后术后并发症的影响
José Ignacio Nolazco1, Kevin R Melnick2, Jeffrey Che-Wei Chang3
1Department of Urology, Mass General Brigham, Harvard Medical School, Boston, MA; Servicio de Urología, Hospital Universitario Austral, Universidad Austral, Pilar, Argentina.
Urologic oncology
|March 20, 2025
概括
烟草使用显著增加了轻微和重大并发症的风险,包括死亡率,部分切除术后. 手术前的戒烟计划对于改善手术后患者的治疗结果至关重要.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 公共卫生 公共卫生
背景情况:
- 烟草使用是已知的手术并发症的风险因素.
- 烟草使用对部分切除术后结果的具体影响需要进一步研究.
研究的目的:
- 调查吸烟与部分切除术后90天术后并发症的发生率和严重程度之间的关联.
- 评估烟草使用对部分切除术后90天死亡率的影响.
主要方法:
- 使用Premier医疗保健数据库 (2010-2019) 进行的横截面研究.
- 主要结局:使用Dindo-Clavien系统评估90天的术后并发症.
- 多项逻辑回归调整了混因子,以估计烟草使用与并发症风险之间的关联.
主要成果:
- 分析包括44392名接受选择性部分切除术的患者;36.15%是烟草使用者.
- 烟草使用者出现小 (OR 1.19) 和大 (OR 1.41) 90天术后并发症的几率显著增加.
- 烟草使用也与90天死亡率增加的几率有关 (OR 1.5).
结论:
- 烟草使用是部分切除术后轻微和重大术后并发症和死亡率增加的重要独立风险因素.
- 研究结果强调,急需进行手术前戒烟干预措施,以减轻手术风险.
- 通过戒烟来优化患者护理可以改善部分切除术患者的结果.
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