在ICU中与肺癌相关的严重血栓塞:复发和结果
Raphael Salvayre1, Clément Hanotin2, Antoine Parrot3
1Assistance Publique-Hôpitaux de Paris (AP-HP), Service de Médecine Intensive Réanimation, Hôpital Tenon, Sorbonne Université, 4 Rue de la Chine, 75020, Paris, France.
肺癌患者的严重血栓塞的复发率很高,预后不佳. 黄金葡萄球菌感染与复发和死亡率有关,这表明抗菌治疗的作用.
科学领域:
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
- 干预性放射学 干预性放射学
背景情况:
- 严重的血 (SH) 是肺癌 (LC) 的关键并发症.
- 管理包括医疗措施和血管干预放射学 (VIR).
- 关于早期出血复发和预后的预测因素的数据有限.
研究的目的:
- 调查与肺癌患者早期出血复发相关的临床和放射性特征,这些患者接受VIR治疗重度血.
- 为了确定这些特征和出血复发的预后意义.
主要方法:
- 对130名SH和LC需要VIR的患者进行了回顾性单中心研究 (2009-2020).
- 对初始临床和放射学数据的分析.
- 评估出血复发和死亡率 (28天,6个月,12个月).
主要成果:
- 在50%的病例中,SH是初始的;下呼吸道感染 (LRTI) 记录在39%的病例中.
- 在VIR.之后,34%的患者出现出血复发.
- 静脉注射terlipressin和LRTI预测复发;瘤腔化,金黄色葡萄球菌感染,以及复发预测死亡率.
结论:
- 与肺癌相关的SH携带出血复发和预后不佳的高风险.
- 黄金葡萄球菌感染与复发和死亡率有关,突出显示了抗菌疗法的潜在益处.
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