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Updated: May 21, 2025

Author Spotlight: Evaluating Biophysical Assays for Characterizing PROTACS Ternary Complexes
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Published on: January 12, 2024

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征服PROTAC的分子设计和可用性

Ritesh P Bhole1,2, Sonali Labhade1, Shilendra S Gurav3

  • 1Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pimpri, Pune, India.

Bioanalysis
|March 21, 2025
PubMed
概括

PROTACs (蛋白质分解向的嵌合体) 实现了向蛋白质降解,彻底改变了对挑战性疾病的药物发现. 分子设计的创新和临床成功表明,PROTACs准备好改变精密医学.

关键词:
人工智能和机器学习招募 E3 酶的方法精准医学是一门精准的医学.免疫疗法 免疫疗法连接体的发现 连接体发现针对性治疗和组合治疗.有针对性的蛋白质降解降解.治疗创新是一种治疗创新.

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