在新辅助化学辐射治疗前计划性胃口的效果在患有内镜阻断性结肠直肠癌的患者中
Zhan-Xiang Hai1, Jun-Nan Zhao1, Xu-Rui Liu1
1The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
在结直肠癌 (CRC) 患者的新辅助化疗 (nCRT) 之前进行计划性静脉栓塞,阻塞会延迟治疗. 这种方法并没有改善生存率,但增加了并发症,这表明需要仔细考虑.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 结直肠癌 (CRC) 中的内镜阻塞存在治疗挑战.
- 新辅助化学辐射 (nCRT) 是局部晚期CRC的标准治疗方法.
- 在nCRT之前的计划性静脉栓在阻断CRC中的作用还不清楚.
研究的目的:
- 为了研究在nCRT前计划性静脉口腔瘤对内镜阻塞结直肠癌患者的结果的影响.
- 为了比较接受静脉栓塞的患者和没有接受静脉栓塞的患者之间的短期和长期结果.
主要方法:
- 从2017年1月到2022年4月,对51名内镜阻塞性CRC患者的回顾性采集.
- 结口组 (n=11) 和没有结口组 (n=40) 之间的基线特征和结果的比较.
- 使用SPSS版本22.0.0进行统计分析.
主要成果:
- 静脉口腔组在启动nCRT方面经历了显著的延迟 (30.6天对11.9天,P <0.05).
- 两组之间观察到并发症的统计学上显著差异 (P < 0.05).
- 在nCRT前计划性静脉栓塞并没有显著影响内镜阻塞CRC患者的存活率 (P > 0.05).
结论:
- 在nCRT之前的计划性静脉瘤延迟了治疗开始,阻碍了CRC.
- 没有口腔口腔组在nCRT期间瘤穿孔或阻塞的可能性更高.
- 综合性评估至关重要,以确定在阻塞CRC时是否需要计划性静脉管.
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