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在老年风湿关节炎患者中,与身体功能和虚弱相关的认知功能障碍
Takeshi Mochizuki1, Koichiro Yano2, Katsunori Ikari2
1Department of Orthopedic Surgery and Rheumatology, Kamagaya General Hospital, Chiba, Japan.
认知功能障碍影响超过四分之一的老年类类风湿性关节炎患者. 年龄,残疾和脆弱是关键的关联因素,强调了综合护理的必要性.
科学领域:
- 类风湿病学 类风湿病学
- 老年学是一门学科.
- 神经科学是一个神经科学.
背景情况:
- 认知功能对于类风湿性关节炎 (RA) 管理和生活质量至关重要.
- 认知障碍可能会阻碍RA患者的治疗坚持和整体幸福感.
研究的目的:
- 确定与老年日本RA患者认知功能障碍相关的因素.
- 为了研究 RA 的认知功能,虚弱和疾病活动之间的关系.
主要方法:
- 452名65岁以上的RA患者使用社区综合护理系统8项 (DASC-8) 痴呆症评估表进行认知功能评估.
- 使用Kihon检查清单 (KCL) 测量脆弱性,患者被分为强壮,脆弱前和脆弱组.
- 多变量逻辑回归分析了与认知障碍相关的因素 (DASC-8分数≥11).
主要成果:
- 认知功能障碍在26.5%的研究人口中普遍存在.
- 相关因素包括年龄较大 (p=0.046),健康评估问卷-残疾指数得分较高 (p<0.001),Kihon检查清单得分增加 (p<0.001).
- 与没有认知障碍的人 (28.6%,p<0.001) 相比,认知障碍者 (85.0%) 的虚弱率明显高于没有认知障碍的人 (28.6%,p<0.001).
结论:
- 认知功能障碍在RA的老年人中很常见,并且与衰老有关.
- 年龄,残疾和虚弱是这一群体认知障碍的重要预测因素.
- 对老年RA患者来说,与RA疾病活动,身体功能和虚弱相结合,认知功能的综合管理至关重要.
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