腰围和BMI对饮食频率和死亡率之间的关联的调节效应
Li-Juan Tan1,2, Sangah Shin2
1Department of Critical Care Medicine, Shanghai Children's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai200062, China.
Public health nutrition
|March 21, 2025
概括
与其他频率相比,每天吃三餐与较低的死亡风险有关. 这一效应部分由腰围介导,这表明食用时间和体重管理的联合策略是有益的.
科学领域:
- 营养流行病学 营养流行病学
- 公共卫生 公共卫生
- 预防慢性疾病 预防慢性疾病
背景情况:
- 饮食频率是一种饮食模式,可能会影响健康结果.
- 肥胖指数,如体重指数 (BMI) 和腰围 (WC),是死亡率的确立风险因素.
- 了解饮食频率,肥胖和死亡率之间的相互作用对于公共卫生战略至关重要.
研究的目的:
- 通过肥胖指数调查饮食频率对死亡率的间接影响.
- 确定饮食频率是否与全因,癌症和心血管疾病 (CVD) 死亡率有关.
- 探索BMI和WC在饮食频率和死亡率之间的关系中的调解作用.
主要方法:
- 一项前性队列研究设计,涉及148,438名40岁以上的韩国成年人.
- 使用经过验证的食物频率问卷 (FFQ) 评估的基线饮食频率.
- 考克斯比例危险回归和中介分析用于检查死亡风险和WC和BMI的中介作用.
主要成果:
- 与每天三餐相比,每天吃一次或四次与更高的全因死亡风险有关.
- 不规则的饮食频率增加了心血管疾病死亡风险,而一天一次或四次增加了癌症死亡风险.
- 增加的腰围部分介导了饮食频率和全因死亡率之间的关联,在因特定原因死亡率方面观察到类似的效应.
结论:
- 每天吃三餐与较低的死亡率和潜在的更长的预期寿命有关.
- 增加的腰围部分介于与低于最佳的饮食频率相关的死亡风险.
- 公共卫生干预措施应考虑同时解决饮食频率和减肥策略.
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