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Updated: May 21, 2025

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

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创建HBD的新Cis调节元件,以重新激活三角球蛋白

Lini Chen1,2, Diandian Liu1,2, Weicong Hong1,2

  • 1Department of Pediatrics, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou, People's Republic of China.

Human gene therapy
|March 21, 2025
PubMed
概括

基因编辑成功地激活了三角球蛋白表达,用于潜在的血液疾病治疗. 在HBD基因调节区域的特定cis作用元素放置是这种治疗方法的关键.

关键词:
在 GATA1 中,GATA1 是 GATA1.一个KLF1一个KLF1在TAL1中,你会看到TAL1.基因组编辑 基因组编辑在β-thalassemia中,的 δ-环球蛋白.

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