使用FACT-C问卷对直肠癌手术后生活质量变化的研究
K Chandramohan1, Mithun Mohandas1, Madhu Muralee1
1Department of Surgical Services, Regional Cancer Centre, Thiruvananthapuram, India.
Indian journal of surgical oncology
|March 21, 2025
概括
结直肠癌手术最初会降低所有领域的生活质量 (QOL). 在一年内,QOL逐渐改善,年轻患者和经过腹腔切除术 (APR) 患者的恢复速度更快.
科学领域:
- 在瘤学瘤学.
- 手术瘤学手术瘤学
- 生活质量研究 研究 生命质量研究
背景情况:
- 结直肠癌治疗,包括新辅助疗法和手术,显著影响患者的生活质量 (QOL).
- 局部晚期直肠癌的手术选择包括关节保护手术 (SPS) 和腹腔切除 (APR).
研究的目的:
- 为了确定接受直肠癌手术的患者的QOL变化模式.
- 用验证的FACT-C (马来语) 问卷来评估QOL.
主要方法:
- 一项前性研究涉及102名接受手术的直肠癌患者.
- 通过使用FACT-C (马来语) 问卷在手术前和手术后1个月,3个月和1年的时间来评估QOL.
- 配对的t测试被用来比较不同时间点和不同患者群体的QOL得分.
主要成果:
- 整体QOL和所有四个领域 (身体,情感,社会,功能福祉) 在手术后1个月显著下降,身体和功能福祉的下降最为深刻.
- 最初,SPS和APR组的QOL得分没有差异,但APR患者的康复速度更快3个月.
- 根据年龄组,性别,手术方法 (腹腔镜/开放),疾病阶段或辅助疗法,没有观察到QOL的显著差异,尽管年轻的患者和女性显示出更快的社会领域改善.
结论:
- 结直肠癌手术导致QOL的初始下降,随后在一年内逐渐改善.
- 与关节保护手术 (SPS) 患者相比,腹腔切除术 (APR) 患者表现出较早的QOL恢复.
- 诸如年龄和手术方法等因素影响了QOL恢复的"模式",年轻患者和APR显示出更快的改善.
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