胸部炎症性肌纤维细胞瘤中对洛拉提尼布的部分反应 隐藏复杂和罕见的ALK融合:一个病例报告
Li-Bo Tang1,2, Ying-Long Peng1,2, Xiao-Rong Yang1,2
1School of Medicine, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou, China.
Translational lung cancer research
|March 21, 2025
概括
第三代ALK氨酸激酶抑制剂 (TKIs) 在治疗复杂ALK重组的晚期炎症性肌纤维细胞瘤 (IMT) 方面表现有前途. 这一案例突出了洛拉提尼布的重要性.
科学领域:
- 在瘤学瘤学.
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
背景情况:
- 炎症性肌纤维细胞瘤 (IMT) 是一种罕见的肉瘤.
- 大约50%的IMT病例涉及形淋巴瘤激酶 (ALK) 基因重组.
- ALK氨酸激酶抑制剂 (TKI) 越来越多地用于ALK融合阳性IMT,但第三代TKI的疗效以前没有得到证实.
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