生命至关重要的9和结石之间的关联:基于人口的研究
Xiao-Ran Li1,2, Han-Lin Liu1,2, Li Wang1,2
1The Second Hospital and Clinical Medical School, Lanzhou University, Lanzhou, China.
Frontiers in medicine
|March 21, 2025
概括
高度生命的关键9 (LC9) 评分与降低结石风险有关. 优化LC9可能是预防结石形成和复发的关键.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 预防医学 预防医学
- 公共卫生 公共卫生
背景情况:
- 结石影响了美国成年人口的很大一部分.
- 生命的关键9 (LC9) 评分是对心血管和代谢健康的综合测量.
- 了解结石的可修改风险因素对于公共卫生倡议至关重要.
研究的目的:
- 研究生命关键9 (LC9) 评分与美国成年人结石患病率之间的关联.
- 为了确定较高的LC9得分是否与较低的结石发病率或复发率相关.
主要方法:
- 对国家健康和营养检查调查 (NHANES) 数据 (2007-2014) 的横截面分析.
- 包括患有石发作或复发的成年参与者.
- 使用加权多变量后勤回归,受限立方线 (RCS) 建模和值效应分析来评估LC9得分和结石患病率之间的关系.
主要成果:
- 总共有24,669名参与者被分析,整体结石患病率为8.45%.
- 每增加一个点的LC9得分与结石发病率下降1.2%有关 (p=0.014).
- 观察到非线性关联,LC9分数的断点为72.777,最高四分位数的复发率明显较低.
结论:
- 较高的LC9得分与结石形成和复发的风险降低有关.
- 保持最佳的LC9得分可能是预防结石的有效策略.
- 种族和痛风被确定为LC9得分-结石关系的显著修饰者.
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