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Updated: May 21, 2025

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes

Published on: May 31, 2018

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在循环pDC中通过EP2和EP4传递PGE2信号的不同作用:对瘤微环境中的免疫调节的影响

Jorge Cuenca-Escalona1, Mark W D Sweep1,2, Mark A J Gorris1

  • 1Department of Medical BioSciences, Radboud University Medical Center, Geert Grooteplein 26-28 6500HB, Nijmegen, the Netherlands.

Journal of leukocyte biology
|March 21, 2025
PubMed
概括

通过EP2和EP4受体发出信号的前列腺素E2 (PGE2) 不同地影响等离子体状树突细胞 (pDCs). 准这些受体可能会逆转瘤诱导的pDC功能障碍,提供治疗潜力.

关键词:
乙质前列腺受体2型受体4型E-prostanoid受体的受体类型 4.血细胞型的 DC 电流.的前列腺素E2E2的前列腺素.瘤微环境是一个微环境.

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