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GZMA静音抑制了JAK2/STAT1通路,并改善了过敏性鼻炎

Lin Li1, Yuhao Zhang1, Jingyuan Wang1

  • 1Department of Otolaryngology Head and Neck Surgery, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, Shanxi, China.

General physiology and biophysics
|March 21, 2025
PubMed
概括

这项研究确定了关键基因,包括参与过敏性鼻炎 (AR) 的Granzyme A (GZMA). 沉默GZMA减少炎症并影响细胞行为,这表明GZMA是AR的潜在治疗点.

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