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Updated: Jul 27, 2026

Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
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在多个维度使用人工智能驱动的高性能化基质对CYP3A4的功能成像

Feng Zhang1, Lilin Song2, Ruixuan Wang1

  • 1State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China.

Small (Weinheim an der Bergstrasse, Germany)
|March 21, 2025
PubMed
概括

研究人员开发了一种人工智能设计的口服活性原基质 (NFa),用于成像细胞染色体P450 3A4 (CYP3A4). 这种新的工具能够对酶活性进行敏感的体内传感,并有助于药物发现.

关键词:
人工智能 (AI) 驱动的分子设计细胞染色体P450 3A4 (CYP3A4) 的使用.化基质的化基质功能成像功能成像功能成像抑制剂查查 抑制剂查

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