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Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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与药物诱导的QT延长相关的药物遗传学标记:系统性审查

Marlene Schouby Bentestuen1,2, Christian Noe Weis3, Caroline Bækmann Jeppesen4

  • 1Psychosis Research Unit, Aarhus University Hospital Psychiatry, Aarhus, Denmark.

Pharmacogenomics
|March 21, 2025
PubMed
概括

这一系统性审查发现药物诱导的QT间隔延长 (diQTP) 的有限一致的药物基因组学 (PGx) 标志物. 未来的研究需要多样化的群体来进行强大的PGx发现.

关键词:
药物诱导的QT延长心脏安全性心脏安全性药物安全 药物安全药物诱导的心律失常是药物引起的.个性化医疗是个性化的医疗.药物遗传学 药物遗传学药物基因组学 药物基因组学

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