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Updated: May 21, 2025

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
12:16

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

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通过深度CD19+细胞枯竭可以治愈自身免疫性疾病吗?

Dan Suan1, John Moore2,3,4, Christopher C Goodnow1,5

  • 1Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

Journal of immunology (Baltimore, Md. : 1950)
|March 21, 2025
PubMed
概括

新的研究表明,针对CD19+血细胞,而不仅仅是CD20,可能为自身免疫性疾病提供持久的缓解. 这种方法解决了当前CD20疗法的局限性,通过向长寿的自身抗体产生细胞.

关键词:
B 细胞 B 细胞 B 细胞在CAR T细胞中,这是自抗体的自抗体.这是自身免疫力.血细胞是血细胞的组成部分.

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