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直接口服抗凝剂的全基因组关联研究及其与出血的关系

Sofia Attelind1,2, Niclas Eriksson3,4, Mia Wadelius3

  • 1Department of Medical Sciences, Clinical Pharmacogenomics, Uppsala University, Uppsala, Sweden. sofia.attelind@medsci.uu.se.

European journal of clinical pharmacology
|March 21, 2025
PubMed
概括

在BAIAP2L2,CYP3A5,ABCG2和VWF基因中的药物基因组变异可能会增加服用直接口服抗凝剂 (DOAC) 的患者的出血风险. 需要进一步的研究来证实这些关联.

关键词:
这就是ABCG2ABCG2.在BAIAP2L2L2中使用.在 CYP3A5A5 中.在VWF中使用VWF.抗凝剂引起的出血是抗凝剂引起的.直接口服抗凝剂 (DOACs) 是一种直接口服抗凝剂.与药物相关的副作用和不良反应全基因组关联研究 (GWAS)

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