Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Difference from Background: Limit of Detection01:05

Difference from Background: Limit of Detection

9.0K
The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...
9.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Proteomic analysis of dental enamel from 20 Homo naledi individuals shows no male markers.

Cell·2026
Same author

Brain structure and function in Homo naledi.

Brain structure & function·2026
Same author

Genomes of the Golden Horde elites and their implications for the rulers of the Mongol Empire.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Epigenetic Age Acceleration and Hearing Function in US Older Adults.

Ear and hearing·2026
Same author

Meaning-making behavior in a small-brained hominin, <i>Homo naledi</i>, from the late Pleistocene: contexts and evolutionary implications.

eLife·2025
Same author

Evidence for deliberate burial of the dead by <i>Homo naledi</i>.

eLife·2025
Same journal

Computational Model for Synthesizing Auditory Brainstem Responses to Assess Neuronal Alterations in Aging and Autistic Animal Models.

Journal of the Association for Research in Otolaryngology : JARO·2026
Same journal

Deaf Acoustics: Listening Through Hearing Aids with Thomas Edison.

Journal of the Association for Research in Otolaryngology : JARO·2026
Same journal

Correction: A Structural Equation Approach to Characterizing Growth and Nonlinearity Underlying Distortion Product Otoacoustic Emissions.

Journal of the Association for Research in Otolaryngology : JARO·2026
Same journal

A Structural Equation Approach to Characterizing Growth and Nonlinearity Underlying Distortion Product Otoacoustic Emissions.

Journal of the Association for Research in Otolaryngology : JARO·2026
Same journal

Age-dependent Shifts in Spiral Ganglion Neuron Subtypes Are Associated with Interphase Gap-dependent Modulation of Electrically Evoked Compound Action Potentials in Mice.

Journal of the Association for Research in Otolaryngology : JARO·2026
Same journal

Bayesian Uncertainty Quantification for A Fractional-Order Model of the Human Ear.

Journal of the Association for Research in Otolaryngology : JARO·2026
查看所有相关文章

相关实验视频

Updated: May 4, 2026

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

10.7K

开发一种校准方法,以最大限度地减少听觉唤起潜力的变化.

Joseph Pinkl1,2,3, Tao Shen4, Jinsai Cheng4

  • 1Department of Research and Development, Gateway Biotechnology Inc., St. Louis, MO, USA. jpinkl@gatewaybiotechnology.com.

Journal of the Association for Research in Otolaryngology : JARO
|March 21, 2025
PubMed
概括
此摘要是机器生成的。

一个新的校准脉冲 (CalPulse) 电路通过减少振幅变化来改善听觉唤起电位 (AEP) 测量. 这种增强的校准准确地检测老年相关的老鼠听力损失,提高诊断灵敏度.

关键词:
听觉脑干反应的响应校准 校准 校准 校准 校准 校准耳突触症 (cochlear synaptopathy) 是一种导致耳突触的疾病.听力损失 听力损失

更多相关视频

Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

16.3K
A Method for Tracking the Time Evolution of Steady-State Evoked Potentials
12:03

A Method for Tracking the Time Evolution of Steady-State Evoked Potentials

Published on: May 25, 2019

8.4K

相关实验视频

Last Updated: May 4, 2026

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities
09:38

Quantitative Assessment of Cortical Auditory-tactile Processing in Children with Disabilities

Published on: January 29, 2014

10.7K
Infant Auditory Processing and Event-related Brain Oscillations
06:34

Infant Auditory Processing and Event-related Brain Oscillations

Published on: July 1, 2015

16.3K
A Method for Tracking the Time Evolution of Steady-State Evoked Potentials
12:03

A Method for Tracking the Time Evolution of Steady-State Evoked Potentials

Published on: May 25, 2019

8.4K

科学领域:

  • 神经科学是一个神经科学.
  • 听觉神经科学 听觉神经科学
  • 生物医学工程 生物医学工程

背景情况:

  • 听觉唤起的潜能 (AEP) 对于评估听觉功能至关重要.
  • 在AEP中幅度的变化可能会阻碍准确的诊断.
  • 需要一种可靠的校准方法来提高AEP测量的一致性.

研究的目的:

  • 开发和验证用于AEP振幅测量的电校准脉冲 (CalPulse) 电路.
  • 为了确定CalPulse信号是否可以作为AEP振幅校准的可靠参考.
  • 评估CalPulse对检测与年龄相关的听觉功能变化的有用性.

主要方法:

  • 将CalPulse电路集成到AEP录音设置中.
  • 在小鼠体外和体外评估CalPulse信号稳定性和可重复性.
  • 使用正弦波CalPulse振幅来使ABR波-1振幅正常化.
  • 在4个月的时间内,正常化与原始ABR波-1幅度的比较变化.

主要成果:

  • 方形和正弦波CalPulse信号在体外都稳定;正弦波在体内表现出更好的重复性.
  • CalPulse 振幅与 ABR 波-1 振幅正相关.
  • 正常化显著降低了波-1幅度的受试者内部变异性.
  • 正常化的振幅在10个月检测到与年龄相关的听力下降,与未校准的振幅不同.

结论:

  • 开发的CalPulse电路有效地减少了AEP振幅的变化.
  • CalPulse为AEP振幅测量提供了可靠的校准参考.
  • 这种方法提高了对听觉功能评估的诊断灵敏度.