异常的手术前血液学查测试是否与异常性脊柱病手术中的全基输血有关?
Vivien Chan1, Suhas Etigunta2, Armaan K Malhotra3
1Spine Center, Cedars-Sinai Medical Center, 444 S San Vicente Blvd, Ste 900, Los Angeles, CA, 90048, USA. Vivien.Chan@cshs.org.
Spine deformity
|March 21, 2025
概括
常规的手术前实验室测试,如INR和血红素,可以帮助预测在儿科脊柱病手术中需要输血的需要. 其他测试,如PTT和血小板计数,没有显示对输血率有重大影响.
科学领域:
- 儿科整形外科 儿科整形外科
- 输血医学 输血医学
- 临床实验室科学 临床实验室科学
背景情况:
- 常规的手术前实验室评估在儿科手术患者的必要性上受到争议.
- 通过后脊髓融合纠正异形脊柱病是儿童常见的手术.
- 异构输血是一种潜在的并发症,需要仔细的手术前评估.
研究的目的:
- 调查手术前实验室测试异常和异构输血之间的关联,在儿童患者接受后脊髓融合为异形脊柱病.
- 为了确定常规的手术前实验室查是否能预测这个特定人群的输血需求.
主要方法:
- 利用了NSQIP儿科数据库 (2016-2022年) 对18岁以下的患者进行后脊髓融合以治疗异常脊椎病.
- 分析了手术前的血红素,白蛋白,血小板计数,国际正常化比率 (INR) 和部分血栓形成时间 (PTT).
- 使用描述性统计,G测试进行比较,以及多变量逻辑回归来评估与异常实验室值相关的输血风险.
主要成果:
- 在6057名患者中,13.6%接受过异构输血.
- 不正常的手术前INR,低血红素 (<35) 和低白蛋白 (<3.4) 与更高的输血率有关.
- 多变量分析证实异常INR (>1.2) 和低血红素 (<35) 显著增加了异构输血的几率.
结论:
- 手术前的INR和血红素水平是分层分层的有价值的工具,用于对儿科患者进行异形脊柱结合治疗的异形脊柱结石症的全基输血风险.
- 在这个队列中,没有发现PTT和血小板计数是术后输血需求的显著预测因素.
更多相关视频
05:23Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
19.3K
08:08Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
Published on: October 16, 2013
10.6K
相关概念视频
01:22Bone Marrow Sampling and Transplants
268
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
268
01:15Blood Transfusion
455
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
455
02:45Blood Transfusion and Agglutination
10.7K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
10.7K