禁食和头痛的原因
Patrick T Ebbert1, Lauren R Natbony2,3
1Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
禁食可能最初会使偏头痛症状恶化. 然而,通过间歇性禁食,性饮食通过降低炎症和改善大脑刺激性来减少偏头痛的频率和严重性的承诺.
科学领域:
- 神经学 神经学
- 代谢研究研究 代谢研究
背景情况:
- 偏头痛是一种复杂的神经系统疾病,对生活质量产生重大影响.
- 代谢因素,包括饮食和禁食在偏头痛病理生理学中的作用是一个新兴的研究领域.
研究的目的:
- 审查有关禁食和偏头痛之间关系的当前文献.
- 检查连接禁食和偏头痛的临床结果和病理生理机制.
主要方法:
- 文献综述综合了最近关于禁食和偏头痛的研究.
- 分析临床试验数据和遗传研究.
主要成果:
- 追溯分析表明,短期禁食可能会加剧偏头痛症状.
- 性饮食显著降低了偏头痛的频率,炎症标志物和残疾 (VAS,MIDAS,HIT-6).
- 性饮食的好处与生成有关,而不是外源体,这表明代谢途径的参与.
- 确定了血糖处理和偏头痛发生之间的遗传联系.
结论:
- 生成似乎通过减少炎症和皮质刺激性来减少偏头痛的频率和残疾.
- 间歇性禁食在预防偏头痛方面的潜力需要进一步的专门研究.
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