植物化物提取的非传统技术:十年的进步 (2014-2023)
Victor Menezes Sipoloni1, Milena Costa Bassicheto1, Maria Vitória de Oliveira2
1Programa de Pós-Graduação em Biologia Química, Instituto de Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, Brazil.
Chemistry & biodiversity
|March 21, 2025
概括
本综述强调了植物化物提取的环保进步,重点关注可持续的方法,如超临界流体提取 (SFE) 和微波辅助提取 (MAE) 用于制药应用.
科学领域:
- 植物生物化学和天然产品化学.
- 可持续的开采技术.
背景情况:
- 植物的二次代谢产生各种各样的类化合物,具有重要的药理价值的生物活性化合物.
- 传统的化物提取方法往往涉及危险的溶剂和低效的过程.
- 历史上的酸提取技术已经被现代,更绿色的替代品所取代.
研究的目的:
- 从2014年到2023年审查植物化物提取方法的演变.
- 强调开发和应用环保的提取技术.
- 突出先进方法在天然产品化学和制药应用中的作用.
主要方法:
- 探索现代提取技术,包括超临界流体提取 (SFE),微波辅助提取 (MAE) 和超声波辅助提取 (UAE).
- 讨论新的溶剂系统,如离子液体 (ILs) 和深度性溶剂 (DESs).
- 分析效率,优化产量,缩短开采时间和减轻环境影响.
主要成果:
- 先进的方法显著提高了化物提取效率,减少了加工时间.
- 环保技术如SFE,MAE,UAE,ILs和DESs可以最大限度地减少溶剂的使用和环境危害.
- 这些方法提供了增强的可持续性,并且在现代天然产品化学中至关重要.
结论:
- 化物提取的演变显示出一个强烈的趋势,朝着可持续和高效的做法.
- 先进的绿色提取技术对于植物性类化合物的未来制药和药物应用至关重要.
- 继续在这一领域的研究对于优化自然产品隔离至关重要.
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