含有益生菌和潘醇的多用途治疗皮肤化品 治疗行动性角质瘤的冷治疗后:随机对照试验的结果
Cesare Ariasi1, Carola Romanò1, Cesare Tomasi1
1Department of Dermatology, University of Brescia, Brescia, Italy.
Dermatology practical & conceptual
|March 21, 2025
概括
一种新的皮肤化品 (DC) 配方显著加快了治疗速度,并在行动性角质炎 (AK) 结冷治疗后改善了皮肤的外观. 这种益生菌治疗减少了40%的愈合时间,并将局部皮肤反应降到最低.
科学领域:
- 皮肤病学 皮肤病学
- 皮肤化品 皮肤化品
- 益生菌配方 益生菌配方
背景情况:
- 行动性角质瘤 (AK) 是一种癌前的皮肤病变,有可能发展为角质细胞癌.
- 低温疗法是AKs的常见治疗方法,通常会导致局部皮肤反应,需要一个愈合期.
研究的目的:
- 评估一种含有益生菌成分的皮肤化品 (DC) 配方在治疗时间和局部皮肤反应 (LSR) 中的疗效.
- 为了比较DC加酸浸泡 (BA) 与单独BA在处理冷治疗后皮肤愈合和反应方面的疗效.
主要方法:
- 面部/头皮AKs的75名成年患者接受了冷治疗.
- 患者被随机分配,接受单独的BA或BA,然后每天DC应用30天.
- 治疗后3天和30天评估了愈合时间,化品结果和LSR.
主要成果:
- BA+DC组的治愈时间减少了40% (中位数为7天而不是11.5天).
- 在50%的BA+DC治疗病变中,与仅使用BA治疗的20%相比,获得了优异的化品结果.
- 在BA+DC组中发生了轻度LSR,而仅在BA组中发生了中度LSR.
结论:
- 添加益生菌直流配方显著提高了AKs的冷治疗后愈合.
- DC配方改善了美容效果,并减少了局部皮肤反应.
- 没有报告任何不良事件,这表明益生菌直流治疗的安全性概况有利.
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