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Updated: May 21, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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在翻译中丢失:SLFN11诱导了p53独立的亡

Andrew E H Elia1, Snehanshu Chowdhury1, William R DeNight1

  • 1Department of Radiation Oncology, Krantz Family Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Molecular cell
|March 21, 2025
PubMed
概括

蛋白质SLFN11,一种对DNA损伤敏感性的生物标志物,通过阻断蛋白质合成,触发了被编程的细胞死亡 (细胞亡). 这一过程独立于p53蛋白发生.

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