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Updated: May 23, 2025

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages

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巨细胞的颗粒吸收触发了分叉的转录途径,这些途径可以差异调节炎症和溶酶体基因表达

Isidoro Cobo1, Jessica Murillo-Saich2, Mohnish Alishala3

  • 1Division of Clinical Immunology & Rheumatology, Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; CAMBAC (Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center), University of Alabama at Birmingham, Birmingham, CA, USA.

Immunity
|March 21, 2025
PubMed
概括

暴露于颗粒物会触发明显的巨细胞炎症反应和 lysosomal 基因激活. 一个5'primeAMP激活蛋白激酶 (AMPK) 网络调节 lysosomal 基因,与JNK-AP-1通路独立,驱动炎症.

关键词:
这就是AMPKK.在JNK中,JNK就是JNK.表观遗传调节 表观遗传调节lysosome 溶解酶体是如何形成的巨细胞是什么?巨细胞是什么?颗粒颗粒的粒子是什么转录 转录 是一种转录.

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