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Updated: May 21, 2025

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类风湿性关节炎患者的扩散性大B细胞淋巴瘤与B细胞驱动因素的升高有关,包括CXCL13

Nora Euler1, Erik Hellbacher2, Erik Af Klint1

  • 1Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Center for Molecular Medicine, Stockholm, Sweden.

Clinical immunology (Orlando, Fla.)
|March 21, 2025
PubMed
概括

患有类风湿性关节炎 (RA) 患有扩散性大B细胞淋巴瘤 (DLBCL) 的患者表现出更高水平的特定炎症标志物. 这些升高的标记物,特别是CXCL13,可能会导致RA患者的B细胞激活和淋巴瘤发展.

关键词:
自动抗体是一种自身抗体.B细胞是B细胞的组成部分.在CXCL13中,CXCL13是最重要的.细胞因子 (cytokines) 是一种细胞因子.DLBCL DLBCL 是一个字母.炎症 炎症是一种炎症.淋巴瘤是一种淋巴瘤.类风湿性关节炎 类风湿性关节炎 类风湿性关节炎里图西马布 (Rituximab) 是一种药物.

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