三种不同的双聚合自粘树脂水泥的光聚合和自聚合对细胞活性的影响
Ahmet Tolga Deniz1, Ulviye Şebnem Büyükkaplan2, Burçin Aşkım Gümüş3
1Researcher, Ministry of Health, Antalya, Turkey.
The Journal of prosthetic dentistry
|March 21, 2025
概括
这项研究发现,所有测试的自粘树脂水泥都降低了L929细胞活力. 光聚合水泥的细胞毒性低于自聚合水泥,这表明聚合法对生物相容性有影响.
科学领域:
- 生物材料科学 生物材料科学
- 牙科材料科学 牙科材料科学
- 细胞生物学 细胞生物学
背景情况:
- 双聚合自粘树脂水泥在牙科中广泛使用.
- 缺乏全面的生物相容性数据,特别是关于聚合方法的数据.
- 这些体对细胞活性的细胞毒性需要进一步研究.
研究的目的:
- 评估三种双聚合自粘树脂水泥的体内细胞毒性作用.
- 为了比较光聚合和自聚合方法之间的细胞毒性.
- 用MTT测定来评估对L929小鼠纤维细胞的影响.
主要方法:
- 三种自粘树脂水泥是轻质的或自聚合的.
- 提取物以各种度准备,并用L929细胞进行化.
- 细胞活力通过使用3 - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - 的测试在24小时,48小时和72小时进行评估.
主要成果:
- 所有测试的水泥都显著降低了L929细胞活力 (P<.05).
- 细胞毒性随着提取物度和化时间的增加而增加.
- 光聚合的SpeedCem Plus表现出最少的细胞毒性,而自聚合的Calibra Universal表现出最多的细胞毒性.
结论:
- 所有测试的自粘树脂水泥都显示出显著的细胞毒性.
- 水泥的组成和聚合激活类型影响其细胞毒性潜力.
- 与自聚合相比,光聚合通常会导致更高的细胞活力.
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