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不同半固体作为纳米系统载体的优点和治疗应用

Eman Samy Shalaby¹, Samy I Shalaby², Shaymaa A Ismail³

¹Pharmaceutical Technology Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Giza, Egypt.

Therapeutic delivery

|March 22, 2025

概括

半固体系统通过增加粘度,改善治疗剂的吸收,稳定性和生物可用性来增强纳米颗粒和纳米纤维的局部传递.

科学领域:

制药科学制药科学
纳米技术纳米技术
药物输送系统药物输送系统

背景情况:

纳米技术对于将治疗剂输送到目标地点至关重要.
各种纳米载体系统用于局部注射活性成分.
纳米系统的低粘度限制了吸收,稳定性和生物可用性.

研究的目的:

审查半固体系统作为纳米微粒和纳米粒子载体的作用.
要突出半固体系统如何克服低粘度纳米系统的局限性.
总结最近在使用半固体进行纳米载体输送方面的进展.

主要方法:

作为纳米载体载体的半固体系统的综合文献综述.
分析不同类型的半固体配方.
评估半固体系统在药物输送中的优势.

主要成果:

半固体系统有效地提高了纳米载体配方的粘度.
这些系统显著提高了纳米颗粒和纳米纤维的吸收.
观察到局部施用纳米疗法药物的稳定性和生物可用性得到改善.

结论:

半固体系统是改善局部纳米输送的重要工具.
它们的使用克服了与低粘度纳米系统相关的关键限制.
本综述提供了基于半固体的纳米载体系统进步的最新总结.

关键词:

半固体系统是半固体系统.药物输送是药物输送的过程.纳米颗粒是一种纳米粒子.纳米技术是纳米技术.纳米纤维的纳米纤维.

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