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Updated: May 21, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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HIF1A促进了H3K27ac修饰的缺氧诱导的变化,以促进肌体收缩性

Kaiyuan Ji1, Bolun Wen1, Xiaodi Wang1

  • 1Guangzhou Key Laboratory of Maternal-Fetal Medicine, Institute of Reproductive Health and Perinatology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.

Communications biology
|March 22, 2025
PubMed
概括

在分娩期间的缺氧会通过改变基因表达和基因素修饰来加剧肌体收缩. 缺氧诱导因子1-alpha (HIF1A) 调解这些表观遗传变化,为分娩障碍提供潜在的治疗点.

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