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Updated: May 21, 2025

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KLHL25-ACLY模块在 iTreg/Th17 的分化命运确定过程中起到关键作用

Miaomiao Tian1, Fengqi Hao1,2, Xin Jin1

  • 1Key Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, Changchun, Jilin, China.

Communications biology
|March 22, 2025
PubMed
概括

帮助T细胞分化为iTreg或Th17细胞取决于脂肪酸代谢. 一个由TGFβ1和IL-6信号调节的新型KLHL25-ACLY分子开关,决定了这种代谢重编程和细胞命运.

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