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在疾病诊断中保留糖酶的基于活动的分析及其在药物发现中的应用

Yevhenii Radchenko1, Johannes M F G Aerts1, Gideon J Davies2

  • 1Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.

Handbook of experimental pharmacology
|March 22, 2025
PubMed
概括

研究人员开发了基于活动的探针来保留糖化酶,灵感来自环利托. 这些探针有助于疾病诊断和药物发现,治疗癌症和溶酶体储存障碍等疾病.

关键词:
基于活动的蛋白质概况.环利托尔 (Cyclophellitol) 是一种环利托尔 (Cyclophellitol) 的一种类型.葡萄糖仿制剂的使用方法葡萄糖糖酸酶 (Glycosidases) 是一种溶酶体储存障碍 溶酶体储存障碍基于机制的抑制剂 基于机制的抑制剂

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