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Cerebellar Regional Dissection for Molecular Analysis
Published on: December 5, 2020
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成年开始的大脑炎和儿童大脑炎之间有什么区别吗?
Rahşan Göçmen1, Bahar Gülmez2, Onur Ege Tarı3
1Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Türkiye. rgocmen@gmail.com.
概括
成人发病的急性小脑炎 (AC) 与儿童呈现的不同,往往具有严重的后果. 这个最大的病例系列突出了各种原因,以及需要在AC成年人中进行彻底的诊断.
科学领域:
- 神经学 神经学
- 神经炎症是一种神经炎症.
- 小脑疾病 小脑疾病
背景情况:
- 急性小脑炎 (AC) 是一种罕见的小脑炎症,通常在患有传染病,后传染病或自身免疫病因的儿童中出现.
- 儿科AC通常具有良性,自我限制的过程.
研究的目的:
- 描述成人发病AC的临床,实验室和成像特征.
- 将成年人AC特征与现有的儿科文献进行比较.
- 为了确定成人AC的潜在原因和结果.
主要方法:
- 根据临床和放射学发现,对16名被诊断患有AC的成年患者进行了回顾性分析.
- 对患者数据的审查,包括症状,实验室结果和MRI发现.
- 对AC病因的分类 (瘤性,传染性,自身免疫性等). ) 的情况.
主要成果:
- 这项研究包括16名患有AC的成年人 (平均年龄为39.5岁).
- 原因包括瘤性,后感染性,传染性,抗GAD和血细胞性淋巴细胞细胞瘤.
- 常见的症状:意识变化,肌痛发作,心动不良,吐,发烧,头痛,发作.
- 在所有病例中,MRI显示了双边小脑皮层的干涉;3人有出血.
- 在56%的患者中发生了严重的后果,31%的患者死亡.
结论:
- 与儿科病例相比,成人发病的AC表现出明显的特征.
- 病因在成年人中是多样化的,包括神经瘤和自身免疫.
- 成人AC可以导致严重的神经缺陷和显著的死亡率.
- 一个全面的诊断策略对于管理成人AC至关重要.
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