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治疗视觉缺陷的非侵入性脑刺激:系统性审查和元分析

Ahmed W Abbas¹, Heba Aboeldahab², Mohamed Abo Zeid³

¹Faculty of Medicine, Mansoura University, Mansoura, Egypt. dr.ahmedw1267hh@gmail.com.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

|March 22, 2025

概括

重复的跨轨道交替电流刺激 (rTACS) 显示出改善视野检测准确度的希望在同名的半视障患者中. 需要进一步的大规模研究来确认所有视觉功能结果的有效性.

科学领域:

神经科学是一个神经科学.
眼科医生眼科眼科
康复医学康复医学康复医学

背景情况:

视野缺陷 (VFD),包括同名的眼视障碍,是中风或视神经病变的结果.
非侵入性脑刺激 (NIBS) 是一种新兴的VFD管理技术.
目前正在研究用于视觉康复的反复转轨交替电流刺激 (rTACS).

研究的目的:

评估rTACS在患有视力缺陷的患者中的疗效,特别是同名的视力缺陷.
评估rTACS对各种视觉功能参数的影响.

主要方法:

在主要数据库 (PubMed,Embase,Cochrane,Scopus) 进行了系统的文献搜索,截至2023年9月.
确定了相关的随机对照试验 (RCT),提取数据并进行分析.
聚合平均差异计算了高分辨率周边测量精度 (HRP DA),固定精度 (HRP FA),静态自动周边测量叶值 (SAP FT) 和视力敏度 (VA).

主要成果:

对4项RCT的分析表明,与假刺激相比,rTACS显著改善了HRP DA (SMD = 0.35,P = 0.048).
对于HRP FA,SAP FT和近视VA,没有观察到rTACS和假装组之间的显著差异.
趋势表明,在平均值值方面存在潜在的好处,尽管在统计学上并不显著.

结论:

rTACS显示出作为同名半视障碍治疗方法的潜力,特别是增强HRP DA.
虽然一些结果没有达到统计学意义,但这些发现支持需要更大规模的RCT和延长后续.
需要进一步的研究,以充分阐明rTACS在视野缺陷康复中的治疗作用.

关键词:

大脑刺激刺激大脑固定准确度固定准确度固定准确度同一个名字的 hemianopia.视野缺陷视野缺陷视野缺陷

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