关于尼泊尔儿童急性链球菌后球膜炎的叙述性综述
Ajaya Kumar Dhakal1, Devendra Shrestha2, Divya Kc2
1Department of Paediatrics, KIST Medical College and Teaching Hospital, Imadol, Lalitpur, Nepal. ajayakdhakal@gmail.com.
BMC nephrology
|March 22, 2025
概括
急性链球菌后球腺炎 (APSGN) 是尼泊尔儿科住院的重要原因. 由于测试可访问性有限,诊断挑战仍然存在,这影响了受影响儿童的管理和结果.
科学领域:
- 儿科脏病学 儿科脏病学
- 传染性疾病 传染性疾病
- 发展中国家的公共卫生
背景情况:
- 剧烈的链球菌后球膜炎 (APSGN) 是尼泊尔儿童急性损伤的主要原因.
- 它对儿科医院的入院有着显著的贡献,突出了关键的公共卫生问题.
- 了解当地流行病学趋势对于与受影响较小的地区进行比较至关重要.
研究的目的:
- 审查尼泊尔的链球菌感染和APSGN的现状.
- 分析尼泊尔儿童APSGN的流行病学趋势,诊断挑战和管理策略.
- 提供本地数据,以便与APSGN.全球模式进行比较.
主要方法:
- 使用PubMed,谷歌学者和尼泊尔在线期刊进行了有针对性的文献审查.
- 搜索包括2000年1月至2024年12月期间发表的文章,以及会议摘要和评论.
- 分析的重点是病模式,A组链球菌感染,流行病学,临床特征,管理和16岁以下儿童的结果.
主要成果:
- 审查了34篇文章,发现由于血清和补充检测有限而存在诊断挑战.
- 8-11岁的儿童,主要是男性,受到更严重的影响,主要感染途径是皮肤炎.
- 常见的表现包括,高血压和出血症;并发症从急性损伤到需要置换治疗.
结论:
- 在尼泊尔,APSGN仍然是住院的常见原因,由于测试难以获得,因此存在诊断困难.
- 尼泊尔儿童表现出不同的临床表现,人口结构模式和APSGN的结果.
- 尽管面临挑战,但大多数患者表现出有利的短期脏结果,死亡率低.
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