确定hyperemesis gravidarum和全身炎症标志物之间的关系:一个病例控制研究
Fikriye Işıl Adıgüzel1, Serhat Altınkaya2, Sadık Kükrer3
1Department of Obstetrics and Gynecology, Adana City Training and Research Hospital, Adana, Turkey. aze_isil@hotmail.com.
炎症标志物,如中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR) 和单细胞与淋巴细胞的比率 (MLR) 在妊娠过度 (HEG) 中升高. 这些标志物显示出在孕妇中诊断HEG的潜力.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 免疫学 免疫学 免疫学
背景情况:
- 妊娠中症 (HEG) 是一种严重的怀孕中恶心和吐的形式.
- 系统性炎症在HEG病理生理学中的作用需要进一步研究.
研究的目的:
- 调查HEG和特定炎症标志物之间的关系:中性粒细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR) 和单细胞与淋巴细胞的比率 (MLR).
主要方法:
- 一个病例控制研究,涉及150名孕妇与HEG和150名对照.
- 分析包括人口统计数据,全血细胞计数和尿尿水平.
主要成果:
- 与对照组相比,HEG组的NLR,PLR和MLR显著高于对照组 (p <0.05).
- 这些标记在接收器操作特征 (ROC) 分析中显示出适度的区分能力.
- 没有观察到炎症标志物与尿严重程度之间的相关性.
结论:
- 升高的NLR,PLR和MLR表明在HEG中系统性炎症的作用.
- 这些炎症标志物可以在临床实践中作为HEG的潜在辅助诊断工具.
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