对药剂师处方的尼马特里尔维尔/里托纳维尔对COVID-19患者的评估
Jason Srey1, Samantha Divan1, Andrew J Sowles2
1College of Pharmacy, Oregon State University, Corvallis, OR, USA.
概括
药剂师驱动的服务显著改善了对COVID-19患者的尼尔马特里尔维尔/里托纳维尔的适当处方. 这种方法确保了复杂的健康需求和多种药物的个人更安全的药物管理.
科学领域:
- 药理学和临床药学 药理学和临床药学
- 传染性疾病 传染性疾病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 尼尔马特里尔维尔/里托纳维尔是COVID-19的关键门诊治疗方法,但其复杂的处方需要谨慎管理.
- 评估药剂师领导的服务对于优化其在临床实践中的使用至关重要.
研究的目的:
- 通过药剂师驱动的服务与通常护理对比尼马特里尔维尔/里托纳维尔处方的适当性.
- 评估药剂师干预对药物的安全性和有效性的影响.
主要方法:
- 追溯队列研究,比较药剂师处方的尼马特里尔维尔/里托纳维尔与常规护理处方.
- 主要结局:根据授权,肝/功能和药物相互作用,适当处方的患者比例.
- 在2022年5月至12月期间接受涅马特里尔维尔/里托纳维尔的患者的时间匹配.
主要成果:
- 药剂师驱动的护理导致88.7%的尼马特里尔维尔/里托纳维尔处方适当,而在通常护理中为41.5% (P < 0.0001).
- 药剂师更一致地确保了当前的肝脏/脏实验室值,并有效地管理了药物相互作用.
- 及时启动治疗和适当的患者选择并发性疾病在两组都是一致的.
结论:
- 药剂师驱动的服务显著提高了尼尔马特里尔维尔/里托纳维尔的适当处方.
- 药剂师在确保尼马特里尔维尔/里托纳维尔的安全有效使用方面发挥着至关重要的作用,特别是在复杂药物治疗方案和并发症患者中.
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