使用计算机断层扫描和扩散加权全身成像,在类风湿性关节炎中进行恶性查的成像评估,并使用背景身体信号抑制进行全身成像
Takeshi Mochizuki1, Koichiro Yano2, Katsunori Ikari2
1Department of Orthopaedic Surgery, Kamagaya General Hospital, Chiba, Japan.
Modern rheumatology
|March 22, 2025
概括
扩散权重全身成像与背景体信号抑制 (DWIBS) 显示在风湿性关节炎 (RA) 患者的恶性查中,计算机断层扫描 (CT) 的性能优于或相当于计算机断层扫描. 这一发现有助于在RA治疗中进行癌症查和治疗.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 类风湿病学 类风湿病学
背景情况:
- 类风湿性关节炎 (RA) 患者患恶性瘤的风险增加.
- 早期癌症检测对于改善RA患者的治疗结果至关重要.
- 标准的成像方法在全面的癌症查中可能存在局限性.
研究的目的:
- 为了比较从普通计算机断层扫描 (CT) 和扩散加权全身成像与背景身体信号抑制 (DWIBS) 获得的诊断信息,用于关节炎 (RA) 患者的恶性查.
- 评估DWIBS在这个患者群体中作为CT的潜在替代方案或辅助方案的有效性.
主要方法:
- 一组由524名RA患者组成的队列在三个月的间隔内接受了普通CT (胸部到骨盆) 和DWIBS.
- 图像由风湿病学家,放射学家和肺病学家独立解释.
- 分析了这两种恶性瘤检测方式的敏感性和特异性.
主要成果:
- 总体恶性瘤患病率为3.1%,检测到各种癌症.
- 与CT (75.0%) 相比,DWIBS在恶性瘤检测方面表现出更高的灵敏度 (93.8%),尽管在统计学上并不显著 (P = 0.333).
- 与CT (76.0%) 相比,DWIBS的特异性 (85.8%) 显著更高 (P < 0.001).
- CT检测出其他疾病,如间歇性肺病 (17.6%) 和结肠分离体 (27.1%).
结论:
- 在RA患者的恶性查中,DWIBS似乎优于或相当于普通CT.
- 这些发现对优化RA管理中的基于成像的癌症查策略具有重要意义.
- 使用DWIBS可以提高恶性瘤的检测,并有助于解决RA患者的癌症相关问题.
相关概念视频
X-ray Imaging
5.2K
German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...
5.2K
Imaging Studies I: CT and MRI
150
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
150
Magnetic Resonance Imaging
4.9K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
4.9K
Computed Tomography
4.2K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
4.2K
Imaging Studies II: Positron Emission Tomography and Scintigraphy
63
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
63
Radiological Investigation I: X-ray and CT
197
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
197


