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Updated: May 21, 2025

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
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重新评估可接受摄入量:对N-Nitrosomorpholine和N-Nitroso Reboxetine功能的比较研究

Shaofei Zhang1, Jennifer Cheung1, Jakub Kostal2,3

  • 1Pfizer Research, Development, and Medical, Groton, Connecticut, USA.

Environmental and molecular mutagenesis
|March 22, 2025
PubMed
概括

这项研究评估了N-nitroso reboxetine与N-nitrosomorpholine (NMOR) 相比的基因毒性潜力. 尼托罗斯基表现出明显较低的突变致病潜力,这表明该杂质的可接受摄入限值较高.

关键词:
这是TGR的TGR.彗星 彗星 彗星 彗星双重测序是指双重的测序.突变性 突变性 突变性尼托胺是一种氨酸.预测建模预测建模量子力学的量子力学是什么

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