两个ME/CFS和长期COVID患者样本中的认知障碍:比较分析
Zoe Sirotiak1,2, Jenna L Adamowicz3,4, Emily B K Thomas5
1Iowa State University, Ames, IA, USA. zmsiro@iastate.edu.
Journal of clinical psychology in medical settings
|March 22, 2025
概括
患有肌痛性脑筋炎/慢性疲劳综合征 (ME/CFS) 和长期COVID的个人经历显著的认知障碍. 患有ME/CFS的人,特别是长期COVID同时发生的人,面临更高的记忆力和注意力集中问题的风险.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 认知障碍,如记忆和注意力缺陷,在肌痛性脑膜炎/慢性疲劳综合征 (ME/CFS) 和长期COVID中普遍存在.
- 这些情况的同时发生很频繁,但认知困难的独特模式仍未得到充分探索.
研究的目的:
- 研究患有或没有ME/CFS和长期COVID的个体的认知障碍的患病率和类型.
- 为了比较四个组的认知困难:仅ME/CFS,仅COVID长期,两种情况,没有.
主要方法:
- 分析了2022年和2023年国家健康访谈调查数据,分别涵盖了27,512和29,404名美国成年人.
- 利用调查权重和差异估计变量进行可靠的统计分析.
- 应用多变量逻辑回归模型来评估认知困难的可能性,控制社会人口统计和条件之间的共享差异.
主要成果:
- 无论是ME/CFS (调整后的几率比率[aOR] 6.18-5.33) 还是长期COVID (aOR 2.01-2.16) 在调整其他因素后都与认知困难有显著的关联.
- 患有ME/CFS的个体,特别是那些也被诊断为长期COVID的个体,表现出明显易受记忆和注意力集中问题的敏感性.
- 该研究对社会人口统计学因素和其他疾病的存在进行了控制,加强了研究结果.
结论:
- ME/CFS和长期COVID独立地与增加认知障碍的几率有关.
- 伴并发性ME/CFS和长期COVID会增加认知障碍的风险,特别是影响记忆和注意力.
- 研究结果强调了这些疾病对认知功能的重大影响,并强调了针对性干预的必要性.
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