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Updated: Jun 22, 2026

Protocols for Implementing an Escherichia coli Based TX-TL Cell-Free Expression System for Synthetic Biology
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构建基因工程大肠杆菌对L-Threo-3-Hydroxyaspartic酸的De Novo生产进行基因工程

Jing Guo1,2,3, Jiayi Cui4, Mingyue Xun4

  • 1CAS Key Laboratory of Bio-Based Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, 266101, China. guojing@qibebt.ac.cn.

Applied biochemistry and biotechnology
|March 22, 2025
PubMed
概括

这项研究设计了大肠杆菌从葡萄糖中产生新的L-threo-3-hydroxyaspartic acid (L-THA). 工程菌株的最终度为2.87g/L,证明了工业L-THA生物合成的可行发酵平台.

关键词:
埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.新生生物合成的新生生物合成在L-threo-3-Hydroxyaspartic酸中.代谢工程是代谢工程.

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